PayPal’s David Knox joins Hyperion DeFi as CFO

Hyperion DeFi Inc., a company leveraging a digital asset treasury strategy, has appointed David Knox, former head of capital markets at PayPal Holdings Inc., as chief financial officer.
Knox, 36, spent the past 18 months leading PayPal’s finance division for lending and financial services. Before that, he held roles at SoFi Technologies and Cantor Fitzgerald, focusing on securitization and structured transactions.
According to Knox, his decision to join was driven by a deep dive into the crypto sector:
The company’s core strategy centers on building reserves in cryptocurrencies, including HYPE, the native token of the decentralized exchange Hyperliquid, which has surged more than 700% since launch. Hyperion follows the “crypto treasuries” trend initiated by Michael Saylor’s Strategy Inc. but is now competing with dozens of similar issuers.
Knox’s appointment is expected to strengthen Hyperion’s position amid sector volatility: while many crypto treasury firms have seen double-digit stock declines, Hyperion remains among the leaders.
According to Knox, his decision to join was driven by a deep dive into the crypto sector:
I immersed myself in understanding Hyperliquid and the crypto market. This is an opportunity I am unlikely to encounter again in my career.
David Knox’s LinkedIn profile already lists “Hyperion DeFi” as his current workplace. Source: linkedin.com
Hyperion DeFi, formerly known as Eyenovia Inc., pivoted away from its biotech business in the summer 2025 and relaunched as a crypto treasury company. Since then, its Nasdaq-listed shares have climbed more than 400%, and the firm has raised about $50 million in fresh capital.
The company’s core strategy centers on building reserves in cryptocurrencies, including HYPE, the native token of the decentralized exchange Hyperliquid, which has surged more than 700% since launch. Hyperion follows the “crypto treasuries” trend initiated by Michael Saylor’s Strategy Inc. but is now competing with dozens of similar issuers.
Knox’s appointment is expected to strengthen Hyperion’s position amid sector volatility: while many crypto treasury firms have seen double-digit stock declines, Hyperion remains among the leaders.
